Aerial view of a small city with historic brick buildings, tree-lined streets, and a river with bridges in the background under a clear sky.
Portsmouth's newest upscale, apartel accommodation is the Treadwell Mansion, in the foregrouind above, steps from Market Square

Portsmouth Hotel Accommodations

It is impossible to pick a winner among Portsmouth’s five modern, in-town, nationally flagged hotels, all located within several blocks of each other in the picturesque downtown, and each highly recommended by our editors. 

The AC is the newest, the Sheraton is the only real harbor front property, the Hampton Inn and the Residence Inn, located across the street from each other on Portwalk Place, are a few steps closer to the downtown shopping and dining district, and the very nice Hilton Garden Inn is located on The Hill, a cluster of historic homes. The Hotel Thaxter is a luxury 15-room boutique hotel offering stylish, modern accommodations.  The Treadwell Mansion, pictured above, is a newly opened, upscale, historic boutique accommodation in the center of downtown Portsmouth, offering modern, luxury, apartment-style suites just steps from Market Square.

 

Two Stunning New Boutique Hotels, Opened in December, 2022 and August, 2025.

The Treadwell Mansion provides a refined blend of historic character and modern luxury. Guests are just a short walk from vibrant local landmarks, including Market Square, The Music Hall, and the historic Strawbery Banke Museum while offering a comfortable, private retreat ideal for both quick getaways and extended stays.  (MAP

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The palpably deluxe, 15-room Hotel Thaxter opened at 15 Middle Street, Portsmouth in December, 2022, in a carefully restored brick heritage building next door to the John Paul Jones house at the edge of downtown Portsmouth, and in a city brimming with upscale hotel accommodations, it promises to be Portsmouth’s boutique hotel of choice.  (MAP) 

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Downtown Portsmouth’s Big Five Nationally Flagged Hotels


Portsmouth Harborside Hotel
The 180-room Sheraton Portsmouth stands at the Congress Street gateway to the City, a short walk from the downtown retail district, and steps away from some of the City’s best restaurants.  250 Market Street, Portsmouth (MAP

 
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Hilton Garden Inn.
The rather new, three-plus-star, full-service Hilton Garden Inn Portsmouth Downtown, is nestled unobtrusively on “The Hill” amidst a cluster of a dozen or so historic buildings, some dating to the 1700s.  100 High Street, Portsmouth  (MAP)

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AC Hotel by Marriott Portsmouth Waterfront Portsmouth’s newest full-service hotel features a seasonal, outdoor rooftop bar and restaurant and is located within easy walking distance of the Portsmouth waterfront and Market Square, but don’t expect harbor views from its guestrooms.  299 Vaughan St, Portsmouth  (MAP)  

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Residence Inn One of the newer and arguably the nicest hotel in downtown Portsmouth is the Portsmouth Downtown Waterfront Residence Inn, remarkable for its stylish, contemporary, interior décor and a red brick exterior that blends nicely with Portsmouth’s  historic, red brick buildings. 100 Deer St, Portsmouth  (MAP)

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Hampton Inn & Suites Portsmouth Downtown.  Located on Portwalk Place, the contemporary, 120-room Hampton Inn has a saltwater pool, and offers a complimentary self-serve breakfast, and an On-the-Run breakfast bag for guests who arrive in the lobby after 10:30am. 23 Portwalk Place, Portsmouth   (MAP)

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